Advanced Diclofenac Emulgel for Targeted Pain Relief
Diclofenac
| Product dosage: 100mg | |||
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| Product dosage: 50mg | |||
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Diclofenac Emulgel represents a significant advancement in topical analgesic therapy, combining the proven efficacy of diclofenac with innovative emulsion gel technology. This pharmaceutical formulation is specifically engineered to provide targeted relief from musculoskeletal pain and inflammation while minimizing systemic exposure. Developed through extensive clinical research, this emulgel offers healthcare professionals and patients a sophisticated alternative to oral NSAIDs, particularly for localized conditions where direct application is advantageous. Its unique carrier system ensures optimal drug penetration and bioavailability at the site of application.
Features
- Contains diclofenac diethylamine 1.16% w/w (equivalent to 1% diclofenac sodium)
- Advanced emulsion gel technology combining oil and aqueous phases
- pH-balanced formulation (5.0-6.0) compatible with skin physiology
- Rapid penetration enhancers for improved transdermal delivery
- Non-greasy, non-staining, and quick-absorbing base
- Paraben-free and fragrance-free formulation
- Water-miscible base allowing easy removal
- Stable emulsion system preventing phase separation
- Controlled viscosity for optimal application and spreadability
- Preservative system meeting pharmacopeial standards
Benefits
- Provides targeted analgesia directly at the site of pain and inflammation
- Reduces systemic exposure and associated gastrointestinal risks compared to oral NSAIDs
- Offers rapid onset of action through enhanced skin penetration
- Maintains therapeutic drug levels in underlying tissues for sustained relief
- Minimizes risk of systemic drug interactions through localized delivery
- Convenient application without messiness or residue
Common use
This emulgel is indicated for the topical treatment of acute musculoskeletal conditions including strains, sprains, and contusions. It is particularly effective in managing pain and inflammation associated with localized forms of soft tissue rheumatism, osteoarthritis in superficial joints, and sports injuries. The formulation is suitable for application to accessible joints including knees, elbows, wrists, and ankles where direct topical therapy can provide optimal therapeutic benefit.
Dosage and direction
Apply a thin layer of emulgel (approximately 2-4 grams, equivalent to a strip 2-3 inches long) to the affected area 3-4 times daily. Gently massage into the skin until fully absorbed. The total daily dose should not exceed 16 grams of emulgel. Wash hands thoroughly after application unless treating hands. Treatment duration should be limited to 14 days unless otherwise directed by a healthcare professional. Do not apply to broken or damaged skin, and avoid contact with eyes and mucous membranes.
Precautions
Use with caution in patients with history of gastrointestinal disorders, renal impairment, or hepatic dysfunction. Avoid application under occlusive dressings unless specifically directed. Monitor for skin reactions at application site. Exercise caution in elderly patients and those with compromised skin barrier function. Do not apply to large areas of skin or use for prolonged periods without medical supervision. Patients with aspirin-sensitive asthma should use with extreme caution due to potential for cross-sensitivity.
Contraindications
Hypersensitivity to diclofenac, other NSAIDs, or any component of the formulation. Contraindicated in patients with history of asthma, urticaria, or allergic-type reactions precipitated by aspirin or other NSAIDs. Should not be used during the third trimester of pregnancy. Avoid use on eczematous, infected, or broken skin. Not recommended for children under 14 years of age.
Possible side effects
Local reactions including contact dermatitis, itching, redness, dryness, and photosensitivity may occur at application site. Systemic absorption, though minimal, may rarely cause gastrointestinal discomfort, headache, or dizziness. Very rare cases of bronchospasm, angioedema, or anaphylactoid reactions have been reported with topical NSAID use. Discontinue use and seek medical attention if severe skin reactions or systemic symptoms develop.
Drug interaction
Although systemic absorption is low, potential interactions may occur with other NSAIDs, anticoagulants, lithium, methotrexate, cyclosporine, and diuretics. Concurrent use with other topical products may alter absorption characteristics. Monitor patients closely when using with oral NSAIDs or corticosteroids due to potential additive effects.
Missed dose
Apply the missed dose as soon as remembered, unless it is nearly time for the next scheduled application. Do not double the dose to make up for a missed application. Maintain regular application intervals for optimal therapeutic effect.
Overdose
Topical overdose is unlikely due to limited systemic absorption. Excessive application may increase risk of local skin reactions. In case of accidental ingestion, seek immediate medical attention. Symptoms of oral overdose may include nausea, vomiting, headache, drowsiness, and epigastric pain. Supportive and symptomatic treatment is recommended.
Storage
Store at room temperature (15-30°C) in original container. Keep tightly closed when not in use. Protect from light and excessive heat. Do not freeze. Keep out of reach of children and pets. Discard any unused product 6 months after first opening.
Disclaimer
This product should be used only as directed by a healthcare professional. The information provided does not replace medical advice. Patients should consult their physician for diagnosis and appropriate treatment recommendations. Individual results may vary based on condition severity and patient factors.
Reviews
Clinical studies demonstrate significant pain reduction scores compared to placebo (p<0.001) in patients with acute musculoskeletal conditions. Dermatological testing shows excellent skin compatibility with low irritation potential. Patient satisfaction surveys indicate preference over oral NSAIDs for localized pain management due to targeted action and reduced systemic side effects. Healthcare professionals report positive outcomes in managing osteoarthritis pain and sports injuries with this formulation.